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Norfloxacin-d5
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Norfloxacin-d5图片
规格:98%
分子量:324.4
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
诺氟沙星-d5 是氘标记的诺氟沙星。
货号:ajcx23136
CAS:1015856-57-1
分子式:C16H13D5FN3O3
分子量:324.4
溶解度:Chloroform: slightly,DMSO: slightly, heated
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Norfloxacin-d5is intended for use as an internal standard for the quantification of norfloxacin by GC- or LC-MS. Norfloxacin is a fluoroquinolone antibiotic that inhibits the growth of Gram-positive and Gram-negative bacteria (MICs = 4 and 1 μg/ml forS. aureusandP. aeruginosa, respectively).1It also inhibits the growthS. pseudintermedius,S. aureus,E. coli,Pasturella, andS. canisisolates from dogs (mean MIC50s = 0.25, 1, 0.03, 1, and 1 μg/ml, respectively).2Topical administration of norfloxacin (0.1% v/v) reduces corneal ulcer size in a rabbit model ofP. aeruginosacorneal infection. It also prevents encrusted cystitis in bladder and increases survival in a rat model ofCorynebacteriumgroup D2 infection when administered at a dose of 80 mg/kg per day.3Formulations containing norfloxacin have been used to treat urinary tract and gynecological infections.


1.Darrell, R.W., Modak, S.M., and Fox, C.L., Jr.Norfloxacin and silver norfloxacin in the treatment of Pseudomonas corneal ulcer in the rabbit.Trans. Am. Opthalmol. Soc.8275-91(1984) 2.Awji, E.G., Damte, D., Lee, S.-J., et al.The in vitro activity of 15 antimicrobial agents against bacterial isolates from dogsJ. Vet. Med. Sci.74(8)1091-1094(2012) 3.Soriano, F., Rodriguez-Tudela, J.L., Castilla, C., et al.Treatment of encrusted cystitis caused by Corynebacterium group D2 with norfloxacin, ciprofloxacin, and teicoplanin in an experimental model in ratsAntimicrob. Agents Chemother.35(12)2587-2590(1991)