An inhibitor of ASK1
货号:ajcx22030
CAS:2411382-24-4
分子式:C19H19N9O2
分子量：405.4
溶解度:Chloroform: 10 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

CAY10756 is a brain-penetrant inhibitor of apoptosis signal-regulating kinase 1 (ASK1; IC₅₀= 21 nM).¹It inhibits autophosphorylation of ASK1 in HEK293T cells (IC₅₀= 138 nM).

1.Xin, Z., Himmelbauer, K., Jones, J.H., et al.Discovery of CNS-penetrant apoptosis signal-regulating kinase 1 (ASK1) inhibitorsACS Med. Chem. Lett.11(4)485-490(2020)