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15(S)-HETE-d8
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
15(S)-HETE-d8图片
规格:98%
分子量:328.5
包装与价格:
包装价格(元)
25ug电议
50ug电议
100ug电议

产品介绍
An internal standard for the quantification of 15-HETE
货号:ajcx21122
CAS:84807-87-4
分子式:C20H24D8O3
分子量:328.5
溶解度:0.1 M Na2CO3: 2 mg/ml,DMF: Miscible,DMSO: Miscible,Ethanol: Miscible,PBS pH 7.2: 0.8 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

15(S)-HETE-d8contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of 15(S)-HETE by GC-or LC-MS. 15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. In mammals, 15(S)-HETE is synthesized in the respiratory epithelium, leukocytes, and reticulocytes.115(S)-HETE is present in µg/ml concentrations in the nasal secretions of allergic rhinitis.2


1.Nadel, J.A., Conrad, D.J., Ueki, I.F., et al.Immunocytochemical localization of arachidonate 15-lipoxygenase in erythrocyes, leukocytes, and airway cellsJournal of Clinical Investigation871139-1145(1991) 2.Ramis, I., RosellÓ-Catafau, J., Bulbena, O., et al.15-Hydroxyeicosatetraenoic acid as a major eicosanoid in nasal secretions: Assay by high-performance liquid chromatographic-radioimmunoassay and gas chromatographic-mass spectrometric proceduresJournal of Chromatography496416-422(1989)