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Norhyodeoxycholic Acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Norhyodeoxycholic Acid图片
规格:98%
分子量:378.6
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
A synthetic bile acid
货号:ajcx20696
CAS:77518-23-1
分子式:C23H38O4
分子量:378.6
溶解度:DMF: 30mg/mL,DMF:PBS (pH 7.2) (1:1): 0.5mg/mL,DMSO: 20mg/mL,Ethanol: 20mg/mL
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Norhyodeoxycholic acid (NHDCA) is a synthetic bile acid and a derivative of hyodeoxycholic acid .1,2 NHDCA is an intermediate in the synthesis of 3β-sulfooxy-7β-hydroxy-24-nor-5-cholen-23-oic acid, which has been used as an internal standard for the quantification of δ5-bile acid conjugates that have been identified in patients with Niemann-Pick disease type C1.3


|1. Schteingart, C.D., and Hofmann, A.F. Synthesis of 24-nor-5β-cholan-23-oic acid derivatives: A convenient and efficient one-carbon degradation of the side chain of natural bile acids. J. Lipid Res. 29(10), 1387-1395 (1988).|2. Une, M., and Hoshita, T. Natural occurrence and chemical synthesis of bile alcohols, higher bile acids, and short side chain bile acids. Hiroshima J. Med. Sci. 43(2), 37-67 (1994).|3. Kakiyama, G., Muto, A., Shimada, M., et al. Chemical synthesis of 3β-sulfooxy-7β-hydroxy-24-nor-5-cholenoic acid: An internal standard for mass spectrometric analysis of the abnormal δ5-bile acids occurring in Niemann-Pick disease. Steroids 74(9), 766-772 (2009).