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Tipranavir-d4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tipranavir-d4图片
包装:1mg
规格:98%
市场价:4815元
分子量:606.7

产品介绍
An internal standard for the quantification of tipranavir
货号:ajcx20320
CAS:1217819-15-2
分子式:C31H29D4F3N2O5S
分子量:606.7
溶解度:Ethyl Acetate: soluble,Methanol: soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Tipranavir-d4 is intended for use as an internal standard for the quantification of tipranavir by GC- or LC-MS. Tipranavir is a potent, orally bioavailable nonpeptidic HIV aspartyl protease inhibitor (Ki = <1 nM) that prevents cleavage and thus activation of functional HIV-cleaved proteins.1,2 Formulations containing tipranavir, in combination with other HIV treatments, are effective against multidrug resistant viruses and are used in the treatment of HIV infection progression in patients who have not responded well to initial treatments.


|1. Thaisrivongs, S., and Strohbach, J.W. Structure-based discovery of Tipranavir disodium (PNU-140690E): A potent, orally bioavailable, nonpeptidic HIV protease inhibitor. Biopoly. 51(1), 51-58 (1999).|2. Turner, S.R., Strohbach, J.W., Tommasi, R.A., et al. Tipranavir (PNU-140690): A potent, orally bioavailable nonpeptidic HIV protease inhibitor of the 5,6-dihydro-4-hydroxy-2-pyrone sulfonamide class. J. Med. Chem. 41(18), 3467-3476 (1998).