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MGR1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
MGR1图片
规格:98%
分子量:368.4
包装与价格:
包装价格(元)
500ug电议
1mg电议

产品介绍
C22H24O5
货号:ajcx19526
CAS:2361529-46-4
分子式:C22H24O5
分子量:368.4
溶解度:DMF: 30 mg/mL,DMSO: 30 mg/mL,Ethanol: 30 mg/mL
纯度:98%
存储:Store at -20°C
库存:现货

Background:

MGR1 is a probe that generates reactive oxygen species (ROS).1 Upon activation by esterases, MGR1 produces superoxide in vitro, an effect that is reversed by superoxide dismutase (SOD). MGR1 produces ROS and increases production of oxidized phosphatidylserine species in HEK293T cells. It reduces viability of HEK293T cells (IC50s = 5.1-6.3 μM).

参考文献
1. Kelkar, D., Ravikumar, G., Mehendale, N., et al. A chemical-genetic screen identifies ABHD12 as an oxidized-phosphatidylserine lipase. Nat. Chem. Biol. 15(2), 169-178 (2019).