KCC2 blocker 1 是一种口服有效的，选择性的 K+-Cl- 共转运蛋白 KCC2 阻滞剂，IC50 为 1 μM。KCC2 blocker 1 是一种脯氨酸苄酯，具有抗癫痫作用。
货号:ajcx16846
CAS:1228439-36-8
分子式:C22H25NO5S
分子量：415.5
溶解度:DMSO: 250 mg/mL (601.68 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

KCC2 blocker 1 is an orally active and selective K+-Cl- cotransporter KCC2 blocker with an IC50 of 1 μM. KCC2 blocker 1 is a benzyl prolinate and has antiepileptic effect[1].

[1]. PÉgurier C, et al. Benzyl prolinate derivatives as novel selective KCC2 blockers. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2542-5.