VBIT-12 是一种有效的 VDAC1 抑制剂。VBIT-12 直接与 VDAC1 相互作用并阻止 VDAC1 寡聚，从而抑制 VDAC1 的凋亡 (apoptotic) 作用。
货号:ajcx16668
CAS:2089227-65-4
分子式:C25H27N3O3
分子量：417.5
溶解度:DMSO: 250 mg/mL (598.80 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

VBIT-12 is a potent VDAC1 inhibitor. VBIT-12 directly interacts with VDAC1 and prevents VDAC1 oligomerization, and thus inhibits apoptotic action of VDAC1[1].

[1]. Shoshan-Barmatz V, et al. VDAC1, mitochondrial dysfunction, and Alzheimer’s disease. Pharmacol Res. 2018 May;131:87-101.