SMARCA-BD ligand 1 for Protac dihydrochloride 是一种能够与 BAF ATPase 亚基 SMARCA2 结合的化合物,基于 PROTAC 技术,使 SMARCA2 降解。
货号:ajcx16116
CAS:2369053-68-7
分子式:C14H19Cl2N5O
分子量:344.24
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
SMARCA-BD ligand 1 for Protac dihydrochloride is a compound that binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC[1].
[1]. Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680.