L-Carnitine hydrochloride 是一种高度极性的小两性离子，是线粒体β-氧化途径的重要共因子。L-Carnitine hydrochloride 的作用是将长链脂肪酰基辅酶 A 转运到线粒体中，通过 β-氧化降解。L-Carnitine hydrochloride 是一种抗氧化剂。L-Carnitine hydrochloride 可以改善许多先天性代谢错误的代谢失衡。
货号:ajcx15624
CAS:6645-46-1
分子式:C7H16ClNO3
分子量：197.66
溶解度:H2O: 250 mg/mL (1264.80 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism[1][2][3].

L-Carnitine hydrochloride ((R)-Carnitine hydrochloride) (125, 250 mg/kg; i.p.) has a more pronounced bronchodilator effect in this chronic murine asthma model, and decreases urinary LTE4 excretion[4]. Animal Model: 8- to 10-weeks-old and weighed 28-30g BALB/c mice[4]

[1]. Agarwal A, et al. Role of L-carnitine in female infertility. eprod Biol Endocrinol. 2018 Jan 26;16(1):5. [2]. Ferreira GC, et al. L-Carnitine and Acetyl-L-carnitine Roles and Neuroprotection in Developing Brain. Neurochem Res. 2017 Jun;42(6):1661-1675. [3]. Ferreira GC, et al. L-Carnitine and Acetyl-L-carnitine Roles and Neuroprotection in Developing Brain. Neurochem Res. 2017 Jun;42(6):1661-1675. [4]. Uzuner N, et al. The role of L-carnitine in treatment of a murine model of asthma. Acta Med Okayama. 2002 Dec;56(6):295-301.