N3-C5-NHS ester 是一种不可降解的 ADC linker,可用于合成抗体-药物偶联物 (ADCs)。
货号:ajcx14644
CAS:866363-70-4
分子式:C10H14N4O4
分子量:254.24
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
N3-C5-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
[1]. Pyrrolobenzodiazepine Dimer Antibody-Drug Conjugates: Synthesis and Evaluation of Noncleavable Drug-Linkers. J Med Chem. 2017 Dec 14;60(23):9490-9507.