DBCO-PEG4-VA-PBD 是一种抗体偶联药物,由抗肿瘤抗生素 Pyrrolobenzodiazepine (PBD) 和 DBCO-PEG4-VA 连接而成。
货号:ajcx37716
CAS:2241644-09-5
分子式:C80H87N9O16
分子量:1430.6
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
DBCO-PEG4-VA-PBD is a drug-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via DBCO-PEG4-VA[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.