Etavopivat 是一种有效的、选择性的、口服生物可利用的红细胞 (RBC) 丙酮酸激酶 (PKR) 激活剂,具有有效的抗镰刀化作用。
货号:ajcx37594
CAS:2245053-57-8
分子式:C22H23N3O6S
分子量:457.5
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Etavopivat is a potent, selective, orally bioavailable red blood cell (RBC) pyruvate kinase (PKR) activator. Etavopivat has potent antisickling effects[1].
[1]. Shrestha A, et al. FT-4202, an oral PKR activator, has potent antisickling effects and improves RBC survival and Hb levels in SCA mice. Blood Adv. 2021 May 11;5(9):2385-2390.