DBCO-C3-Acid 是一种点击化学 (Click Chemistry) 中间体。DBCO-C3-Acid 可用以合成 ADC linker。
货号:ajcx35440
CAS:1207355-31-4
分子式:C20H17NO3
分子量:319.35
溶解度:DMSO : 100 mg/mL (313.14 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
DBCO-C3-Acid is a Click Chemistry intermediate used in the synthesis of antibody-drug conjugate (ADC) linker[1].
[1]. van Geel R, et al. Chemoenzymatic Conjugation of Toxic Payloads to the Globally Conserved N-Glycan of Native mAbs Provides Homogeneous and Highly Efficacious Antibody-Drug Conjugates. Bioconjug Chem. 2015;26(11):2233-2242.