ARN 077 enantiomer (19) 是ARN 077 的低活性异构体,其对大鼠 NAAA IC50 值为3.53 μM。
货号:ajcx34530
CAS:1439366-88-7
分子式:C16H21NO4
分子量:291.34
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
ARN 077 enantiomer (19) is the less active enantiomer of ARN 077, with an IC50 of 3.53 μM for rat NAAA[1].
[1]. Stefano Ponzano, et al. Synthesis and structure-activity relationship (SAR) of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters, a class of potent N-acylethanolamine acid amidase (NAAA) inhibitors. J Med Chem. 2013 Sep 12;56(17):6917-34.