4-Formylaminoantipyrine 是氨基苯那酮的排泄代谢物 (metabolite)。Aminophenazone 是一种具有镇痛、抗炎、解热作用的吡唑啉酮。
货号:ajcx34442
CAS:1672-58-8
分子式:C12H13N3O2
分子量：231.25
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

4-Formylaminoantipyrine is an excreted metabolite of aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo[1].

[1]. M Levy, et al. Impairment of the metabolism of dipyrone in asymptomatic carriers of the hepatitis B virus. Clin Pharmacol Ther
[2]. A Noda, et al.Formation of 4-formylaminoantipyrine as a new metabolite of aminopyrine. II. Enzymatic demethylation and oxidation of aminopyrine and 4-monomethylaminoantipyrine. Chem Pharm Bull (Tokyo).1976 Dec;24(12):3229-31.
[3]. David do C Malvar, et al. Dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2 -dependent and -independent fever while 4-AA only blocks PGE2 -dependent fever. Br J Pharmacol. 2014 Aug;171(15):3666-79.