GPR30 agonist-1 是一种 G 蛋白偶联受体 30 (GPR30) 激动剂。GPR30 agonist-1 发挥血管舒张作用。
货号:ajcx32512
CAS:415919-74-3
分子式:C19H17BrFNO
分子量：374.25
溶解度:DMSO : 50 mg/mL (133.60 mM; ultrasonic and warming and heat to 80буC)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

GPR30 agonist-1 is a G protein-coupled receptor 30 (GPR30) agonist. GPR30 agonist-1 exerts vasorelaxant effects[1].

GPR30 agonist-1 (compound 5408-0877) (1 nM-10 µM) induces a concentration-dependent relaxation in carotid arteries from both male and female rats. GPR30 agonist-1-induced relaxation is abolished by endothelium removal and abrogated in the presence of the nitric oxide synthase inhibitor NG-nitro-l-arginine methyl ester (100 µM)[1].

参考文献:
[1]. Brad R S Broughton, et al. Endothelium-dependent relaxation by G protein-coupled receptor 30 agonists in rat carotid arteries. Am J Physiol Heart Circ Physiol. 2010 Mar;298(3):H1055-61.