(S)-(+)-O-DesmethylVenlafaxine是O-DesmethylVenlafaxine的S-对映异构体。O-DesmethylVenlafaxine是Venlafaxine的活性代谢产物。Venlafaxine是5-羟色胺-去甲肾上腺素再摄取抑制剂(SNRI)类的抗抑郁剂。
货号:ajcx29834
CAS:142761-12-4
分子式:C16H25NO2
分子量：263.38
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

(S)-(+)-O-Desmethyl Venlafaxine is a S-enantiomer of O-Desmethyl Venlafaxine. O-Desmethyl Venlafaxine is an active metabolite of Venlafaxine[1]. Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class[2].

[1]. Yijin Liu, et al. Development of an enantioselective assay for simultaneous separation of venlafaxine and O-desmethylvenlafaxine by micellar electrokinetic chromatography-tandem mass spectrometry: Application to the analysis of drug-drug interaction. J Chromatogr A. 2015 Nov 13;1420:119-28. [2]. F P Bymaste, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25(6):871-80.