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Pyropheophorbide a methyl ester
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
规格:98%
分子量:548.7
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
A photosensitizer
货号:ajcx26638
CAS:6453-67-4
分子式:C34H36N4O3
分子量:548.7
溶解度:Chloroform: slightly soluble,Methanol: slightly soluble when heated
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Pyropheophorbideamethyl ester is a photosensitizer and a derivative of chlorophylla.1It induces cell death in RIF-1 cells when used in combination with photodynamic therapy (PDT) at concentrations of 0.06 and 1 µM. Pyropheophorbideamethyl ester localizes to cell membranes and induces IL-1 receptor internalization and NF-κB activation following light exposure in HCT116 cells.2

1.Chen, Y., Zheng, X., Dobhal, M.P., et al.Methyl pyropheophorbide-a analogues: Potential fluorescent probes for the peripheral-type benzodiazepine receptor. Effect of central metal in photosensitizing efficacyJ. Med. Chem.48(11)3692-3695(2005) 2.Matroule, J.-Y., Bonizzi, G., MorliÈre, P., et al.Pyropheophorbide-a methyl ester-mediated photosensitization activates transcription factor NF-κB through the interleukin-1 receptor-dependent signaling pathwayJ. Biol. Chem.274(5)2988-3000(1999)