| 规格: | 98% |
| 分子量: | 365.5 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
Background:
GSK 417651A is an inhibitor of transient receptor potential canonical 3 (TRPC3) and TRPC6 (IC50=~0.4 µM for both).1It inhibits migration of isolated human fibroblastic valve interstitial cells into the wounded area in a scratch test assay when used at a concentration of 2 µM.2
1.Xu, X., Lozinskaya, I., Costell, M., et al.Characterization of small molecule TRPC3 and TRPC6 agonist and antagonistsBiophys. J.104(2)454A(2013) 2.Al-Shammari, H., Latif, N., Sarathchandra, P., et al.Expression and function of mechanosensitive ion channels in human valve interstitial cellsPLoS One15(10)e0240532(2020)
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