A penem antibiotic
货号:ajcx25536
CAS:158365-51-6
分子式:C12H14NO5S·Na [2.5H2O]
分子量：352.3
溶解度:DMF: 1 mg/ml,DMSO: 5 mg/ml,PBS (pH 7.2): 10 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Faropenem is a broad-spectrum penem antibiotic.¹It is active against a panel of 12 Gram-positive (MIC₅₀s = 0.008-1 mg/L) and 15 Gram-negative (MIC₅₀s = 0.06-16 mg/L) bacteria. Faropenem (20 mg/kg) reduces the number of lung colony forming units (CFUs) in a mouse model ofH. influenzae-induced respiratory tract infection.²Formulations containing faropenem have been used in the treatment of various bacterial infections.

1.Schurek, K.N., Wiebe, R., Karlowsky, J.a., et al.Faropenem: Review of a new oral penemExpert Rev. Anti. Infect. Ther.5(2)185-198(2007) 2.Miyazaki, S., Hosoyama, T., Furuya, N., et al.In vitro and in vivo antibacterial activities of L-084, a novel oral carbapenem, against causative organisms of respiratory tract infectionsAntimicrob. Agents Chemother.45(1)203-207(2001)