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Prostaglandin E1 isopropyl ester
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Prostaglandin E1 isopropyl ester图片
规格:98%
分子量:396.6
包装与价格:
包装价格(元)
100ug电议
500ug电议
1mg电议
5mg电议

产品介绍
An ester prodrug form of PGE1
货号:ajcx23332
CAS:217182-28-0
分子式:C23H40O5
分子量:396.6
溶解度:DMF: 75 mg/ml,DMSO: 2 mg/ml,Ethanol: 100 mg/ml,PBS (pH 7.2): 50 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Prostaglandin E1isopropyl ester is an ester prodrug form of prostaglandin E1with enhanced lipid solubility.1,2The ester functional group on PGE1isopropyl ester is readily hydrolyzed in cells andin vivoto release active PGE1.1PGE1isopropyl ester exhibits a faster penetration flux than the free acid form of PGE1when applied topically to isolated mouse skin. Topical administration of PGE1isopropyl ester (1 mM) reduces fluid pressure within human dermal fibroblast cell aggregates.2


1.Ho, H.O., Hwang, M.C., Tseng, S.L., et al.The percutaneous penetration of prostaglandin E1 and its alkyl estersJ. Control Release58(3)349-355(1999) 2.Stuhr, L.E., Reith, A., LepsØe, S., et al.Fluid pressure in human dermal fibroblast aggregates measured with micropipettesAm. J. Physiol. Cell Physiol.285(5)C1101-1108(2003)