A building block
货号:ajcx21286
CAS:553-03-7
分子式:C9H9NO
分子量：147.2
溶解度:DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

3,4-Dihydroquinolin-2(1H)-one is a building block.^1,2It has been used in the synthesis of compounds with antidepressant and anticonvulsant activities, as well as dual ligands of sigma (σ) receptors and the NMDA receptor GluN2b subunit that have antioxidant and neuroprotective properties.

1.Deng, X.-Q., Song, M.-X., Zheng, Y., et al.Design, synthesis and evaluation of the antidepressant and anticonvulsant activities of triazole-containing quinolinonesEur. J. Med. Chem.73217-224(2014) 2.Zampieri, D., Fortuna, S., Calabretti, A., et al.Discovery of new potent dual sigma receptor/GluN2b ligands with antioxidant property as neuroprotective agentsEur. J. Med. Chem.180268-282(2019)