Picamilon 是 γ-氨基丁酸的衍生物，具有促智作用 。
货号:ajcx20732
CAS:34562-97-5
分子式:C10H12N2O3
分子量：208.2
溶解度:DMSO: 1 mg/ml,DMSO:PBS (pH 7.2) (1:9): 0.10 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Picamilon is a derivative of γ-aminobutyric acid (GABA).1 It increases parietal cortical blood flow in rats and rabbits when administered at doses of 50 mg/kg, i.p. and 10 mg/kg, i.v., respectively.2 Picamilon (10 mg/kg) increases latency to enter the dark compartment in the passive avoidance conditioned reflex test in rats compared with control animals, indicating nootropic effects.1

|1. Kopelevich, V.M., Bulanova, L.N., Grigor'ev, I.A., et al. Synthesis and study of psychotropic and hypotensive properties of new picamilon derivatives. Pharm. Chem. J. 31(10), 536-539 (1997).|2. Mirzoyan, R.S., Gan'shina, T.S., Kosoi, M.Y., et al. Effect of picamilon on the cerebral cortical blood supply and microcirculation in the pial arteriolar system. Biull. Eksp. Biol. Med. 107(5), 668-670 (1989).