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7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one图片
规格:98%
分子量:342.3
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
C16H10N2O7
货号:ajcx19272
CAS:314742-00-2
分子式:C16H10N2O7
分子量:342.3
溶解度:Chloroform: 30mg/mL,DMF: 30mg/mL,DMF:PBS (pH 7.2) (1:2): 0.30mg/mL,DMSO: 5mg/mL
纯度:98%
存储:Store at -20°C
库存:现货

Background:

7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one is a turn-on fluorescent probe for the detection of hydrogen sulfide (H2S).1 7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one undergoes thiolysis by hydrogen sulfide (HS1-). It displays excitation/emission maxima of 323/445 nm, respectively, in DMSO and its fluorescence intensity increases in the presence of sulfur-containing molecules.2,3,1 7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one is selective for sulfur-containing molecules, including cysteine, glutathione (GSH), homocysteine, and selenocysteine and is not cytotoxic up to a concentration of 150 μg/ml.1,2

参考文献
1. Chen, Y., Shang, X., Li, C., et al. The synthesis, crystal, hydrogen sulfide detection and cell assement of novel chemsensors based on coumarin derivatives. Sci. Rep. 8(1), 16159 (2018).
2. Zhang, B., Ge, C., Yao, J., et al. Selective selenol fluorescent probes: Design, synthesis, structural determinants, and biological applications. J. Am. Chem. Soc. 137(2), 757-769 (2015).
3. Yang, X.F., Su, Z., Liu, C., et al. A thiol-selective fluorogenic probe based on the cleavage of 4-methylumbelliferyl-2',4',6'-trinitropheyl ether. Anal. Bioanal. Chem. 396(7), 2667-2674 (2010).