PROTAC K-Ras Degrader-1 是一种基于 PROTAC 技术的有效的 K-Ras 降解剂,在 SW1573 中对其降解率为 ≥70%。
货号:ajcx15668
CAS:2378258-52-5
分子式:C53H62N10O10
分子量:999.12
溶解度:DMSO: 33.33 mg/mL (33.36 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
PROTAC K-Ras Degrader-1 (Compound 518) is potent K-Ras degrader based PROTAC, exhibits ≥70% degradation efficacy in SW1573 cells[1].
[1]. CREW, Andrew P., et al. MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE. WO2019195609A2.