Olutasidenib是一种突变型异柠檬酸脱氢酶(IDH)1的选择性有效抑制剂,可用于治疗急性髓性白血病。
货号:ajcx12664
CAS:1887014-12-1
分子式:C18H15ClN4O2
分子量:354.79
溶解度:DMSO: 125 mg/mL (352.32 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Olutasidenib is a highly potent, selective inhibitor of mutant Isocitrate dehydrogenase (IDH)1 that could be used in the treatment of acute myeloid leukemia.
[1]. JM Watts, et al. A phase 1 dose escalation study of the IDH1m inhibitor, FT-2102, in patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).