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Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE图片
规格:98%
分子量:1316.58
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE (compound S6) 是一种有效的抗癌剂 (anticancer agent),它可被肿瘤微环境特异性激活。Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE 可抑制小鼠肿瘤生长 (信息来自专利 CN104147612A)。
货号:ajcx39804
CAS:1638970-46-3
分子式:C67H101N11O16
分子量:1316.58
溶解度:DMSO : 180 mg/mL (136.72 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE (compound S6) is a potent anticancer agent, which can be specific activated by tumor microenvironment. Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE can suppress tumor growth in mice (extracted from patent CN104147612A)[1].

Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE (compound S6) (26.2 micro-rubbing/kg, IV, weekly for 4 weeks) suppresses tumor growth in mice bearing Panc-1 tumor[1].

[1]. Liu Chen, et al. Tumor microenvironment specific activated micromolecular targeted conjugate and application thereof. CN104147612A.