VH032 thiol (VHL ligand 6) 是一种 von Hippel-Lindau 蛋白 (VHL) 配体。VH032 thiol (VHL ligand 6) 通过 linker 与 JQ1 结合从而形成 PROTAC 分子。
货号:ajcx39490
CAS:2098836-54-3
分子式:C23H30N4O4S2
分子量：490.64
溶解度:DMSO : 50 mg/mL (101.91 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

VH032 thiol (VHL ligand 6) is a VHL ligand, which binds to pan-BET inhibitor JQ1 via a linker to form PROTAC[1].

[1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.