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α-Methylserotonin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
α-Methylserotonin图片
规格:98%
分子量:190.24
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
α-Methylserotonin 是5-HT2受体的有效和选择性激动剂。α-Methylserotonin 是由α-甲基色氨酸在体内形成的5-羟色胺类似物。α-Methylserotonin 介导淋巴平滑肌收缩并防止血清素受体介导的磷酸肌醇水解的上调。
货号:ajcx37858
CAS:304-52-9
分子式:C11H14N2O
分子量:190.24
溶解度:Methanol : 62.5 mg/mL (328.53 mM; ultrasonic and warming and heat to 60°C)|DMSO : 50 mg/mL (262.83 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

α-Methylserotonin is a potent and selective agonist of 5-HT2 receptor.α-Methylserotonin is an analogue of serotonin formed in vivo from α-methyltryptophan.α-Methylserotonin mediates the lymphatic smooth muscle contraction and prevents the up-regulation of serotonin-receptor-mediated phosphoinositide hydrolysis[1][2][3].

[1]. Dobbins DE. Receptor mechanisms of serotonin-induced prenodal lymphatic constriction in the canine forelimb. Am J Physiol. 1998 Feb;274(2):H650-4.
[2]. Brumley MR, et al. The serotonergic agonists quipazine, CGS-12066A, and alpha-methylserotonin alter motor activity and induce hindlimb stepping in the intact and spinal rat fetus. Behav Neurosci. 2005 Jun;119(3):821-33.
[3]. Edwards E, et al. (+/-)-1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane(DOI) and alpha-methyl-5-HT: 5-HT2 receptor agonistic action on phosphatidylinositol metabolism in the rat fronto-cingulate and entorhinal cortex. Neuropharmacology. 1992 Jul;31(7):615-21.