Pralnacasan (VX-740; HMR-3480) is a novel, potent, selective, and orally bioactive non-peptide inhibitor of caspase 1 (IL-1beta converting enzyme) with a Ki of 1.4 nM and with the potential for the treatment of osteoarthritis and rheumatoid arthritis. It is able to inhibit proinflammatory cytokines IL-18, IL-1β , and IFN-γ.

纯度：≥98%

CAS：192755-52-5