Fmoc-Val-Ala-PAB-OH 是一种可降解 (cleavable) 的 ADC linker,可用于合成抗体偶联药物 (ADC)。
货号:ajcx36364
CAS:1394238-91-5
分子式:C30H33N3O5
分子量:515.6
溶解度:DMSO : 33.33 mg/mL (64.64 mM; ultrasonic and warming and heat to 80°C)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Fmoc-Val-Ala-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.