ABM-14 是一种靶向雄激素受体 (AR) 的配体,用于设计 PROTAC。ABM-14 通过 linker 与 VHL 配体结合形成雄激素受体降解剂 ARCC-4 。
货号:ajcx33630
CAS:1973408-76-2
分子式:C25H18F3N3O2S
分子量:481.49
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
ABM-14 is a ligand for targeting androgen receptor (AR) for PROTAC. ABM-14 binds to a ligand for VHL via linker to form ARCC-4 to degrade AR[1].
[1]. Meizhong Jin, et al. Compounds and methods for the targeted degradation of the androgen receptor. WO2016118666A1.