LM-1685 is a potent and selective inhibitor of COX-2 from human monocytes (IC50 = 650 nM) and in whole blood (IC50 = 4.3 μM). References: Huang KH, Kuo KL, Chen SC, Weng TI, Chuang YT, Tsai YC, Pu YS, Chiang CK, Liu SH. Down-regulation of glucose-regulated protein (GRP) 78 potentiates cytotoxic effect of celecoxib in human urothelial carcinoma cells. PLoS One. 2012;7(3):e33615. doi: 10.1371/journal.pone.0033615. Epub 2012 Mar 16. PubMed PMID: 22438966; PubMed Central PMCID: PMC3306428.

纯度：≥98%

CAS：416901-58-1