C20H16FN7O.HCl
货号:ajcx28046
CAS:N/A
分子式:C20H16FN7O.HCl
分子量：425.85
溶解度:DMSO|42.58|100|
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Promotes proteasomal degradation of Miro1 (mitochondrial Rho GTPase 1). Reduces Miro1 levels in fibroblasts from Parkinson's disease (PD) patients (IC50 = 7.8 μM). Exhibits no significant effect on related outer mitochondrial membrane protein Mitofusin. Reduces stress-induced degeneration of dopaminergic neurons derived from PD patient iPSCs. Rescues age-dependent neuronal loss and prolongs lifespan in fly PD models.