A vasopressin receptor agonist
货号:ajcx25868
CAS:N/A
分子式:C46H64N14O12S2 • XCF3COOH
分子量：1069.2
溶解度:DMF: 1 mg/ml,DMSO: 5 mg/ml,PBS (pH 7.2): 2 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Desmopressin is a synthetic version of the endogenous antidiuretic hormone arginine vasopressin (AVP). Compared to AVP, the first amino acid of desmopressin has been deaminated, and the arginine at the eighth position is in the dextrorotatory rather than the levorotatory form. Desmopressin acts as an agonist at human vasopressin V_1a, V_1b, and V₂receptors with K_ivalues of 62.4, 5.8, and 23.3 nM, respectively.¹

1.Cheng, L.L., Stoev, S., Manning, M., et al.Design of potent and selective agonists for the human vasopressin V1b receptor based on modifications of [deamino-cys1]arginine vasopressin at position 4J. Med. Chem.47(9)2375-2388(2004)