BIZ 114 (Example 11) 是一种脂肪酸衍生物,可有效抑制 TNF-α 激活的 NF-κβ 途径。BIZ 114 可用于眼科疾病(例如视网膜退行性疾病和眼部炎症性疾病)的研究。
货号:ajcx16460
CAS:2099120-74-6
分子式:C24H40O3
分子量:376.57
溶解度:DMSO: 250 mg/mL (663.89 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
BIZ 114 (Example 11) is a fatty acid derivative and potent inhibits the TNF-α activated NF-κβ pathway. BIZ 114 has the potential to prevent and / or treat ophthalmic disorders such as retinal degenerative disorders and ocular inflammatory diseases[1].
[1]. Anne Kristin Holmeide. pid compounds and compositions and their opthalmic use. WO2017093732A1.