HIF-1 inhibitor-1 是一种芳基羧酰胺化合物,是有效的缺氧诱导因子 1 (HIF-1) 抑制剂,其 IC50 值为 0.32 μM,可用于癌症转移。
货号:ajcx16070
CAS:2380261-53-8
分子式:C21H19FN2O2
分子量:350.39
溶解度:DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
纯度:98%
存储:Store at -20°C
库存:
现货Background:
HIF-1 inhibitor-1 is an aryl carboxamide compound and a potent hypoxia-inducible factor 1 (HIF-1) inhibitor with an IC50 of 0.32 μM for the cancer metastasi[1].
[1]. Liu M, et al. Discovery of Novel Aryl Carboxamide Derivatives as Hypoxia-Inducible Factor 1α Signaling Inhibitors with Potent Activities of Anticancer Metastasis. J Med Chem. 2019 Oct 24;62(20):9299-9314.