TAK-831 是一种高度选择性和有效的 D-氨基酸氧化酶 (DAAO) 抑制剂并且可以用于精神分裂症的研究。
货号:ajcx36808
CAS:1425511-32-5
分子式:C13H11F3N2O2
分子量：284.23
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

TAK-831 is a highly selective and potent inhibitor of D-amino acid oxidase (DAAO) and can be used in studies of schizophrenia[1][2].

[1]. Wang H, Norton J, Xu L, DeMartinis N, Sen R, Shah A, Farmer J, Lynch D. Results of a randomized double-blind study evaluating luvadaxistat in adults with Friedreich ataxia. Ann Clin Transl Neurol. 2021 Jun;8(6):1343-1352.
[2]. Yoneyama T, Sato S, Sykes A, Fradley R, Stafford S, Bechar S, Howley E, Patel T, Tagawa Y, Moriwaki T, Asahi S. Mechanistic Multilayer Quantitative Model for Nonlinear Pharmacokinetics, Target Occupancy and Pharmacodynamics (PK/TO/PD) Relationship of D-Amino Acid Oxidase Inhibitor, TAK-831 in Mice. Pharm Res. 2020 Aug 5;37(8):164.