TRPC5 inhibitor
货号:ajcx27632
CAS:N/A
分子式:C15H9BrO5
分子量：349.14
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

TRPC5 inhibitor (IC50 = 0.28 μM); Galangin derivative. Exhibits some selectivity for TRPC5 over TRPC2, 3 and 4. Inhibits effects of TRPC5 activator (-)-Englerin A, but potentiates effects of physiological activators Sphingosine-1-phosphate and LPC.

Naylor et al (2016) Natural and synthetic flavonoid modulation of TRPC5 channels. Br.J.Pharmacol. 173 562 PMID:26565375