N106 是一流的肌质网钙 ATP 酶 (SERCA2a) SUMOylation 激活剂。
货号:ajcx27178
CAS:862974-25-2
分子式:C17H14N4O3S
分子量：354.38
溶解度:DMSO: 20 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Activator of SUMO-activating enzyme, E1 ligase. Increases SERCA2a SUMOylation and activity, and enhances contractility in rat cardiomyocytes in vitro. Improves ventricular function in a mouse model of heart disease.

Kho et al (2015) Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure. Nat.Commun. 6 7229 PMID:26068603