Potent and GluN2A-selective NMDA antagonist
货号:ajcx26902
CAS:N/A
分子式:C17H13BrN3Na4O5P
分子量：542.14
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Potent NMDA receptor antagonist (IC50 = 8 nM). Exhibits >100-fold selectivity for hGluN2A (formally hNR2A) containing receptors over hGluN2B (hNR2B). Anticonvulsant in vivo. Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Auberson et al (2002) 5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition. Bioorg.Med.Chem.Lett. 12 1099 PMID:11909726