A metabolite of prednisolone
货号:ajcx26194
CAS:16355-29-6
分子式:C21H28O6
分子量：376.4
溶解度:DMSO: soluble,Methanol: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

6β-hydroxy Prednisolone is a metabolite of prednisolone , the active metabolite of prednisone .¹It is formed from prednisolone primarily by the cytochrome P450 (CYP) isoform CYP3A4 and to a lesser extent by CYP3A5.

1.Skauby, R.H., Bergan, S., Andersen, A.M., et al.In vitro assessments predict that CYP3A4 contributes to a greater extent than CYP3A5 to prednisolone clearanceBasic Clin. Pharmacol. Toxicol.129(6)427-436(2021)