| 规格: | 98% |
| 分子量: | 421.2 |
| 包装 | 价格(元) |
| 500ug | 电议 |
| 1mg | 电议 |
Background:
Miconazole-d5is intended for use as an internal standard for the quantification of miconazole by GC- or LC-MS. Miconazole is an imidazole antifungal.1It is active againstC. parapsilosis,C. pseudotropicalis,C. albicans,C. neoformans,C. tropicalis, andC. guilliermondii(MICs =<0.1-10 µg/ml). It is also active against variousTrichophytonspecies,A. fumigatus,A. niger,B. brasiliensis, andB. dermatitidis. Miconazole (160 mg/kg) prevents infection withT. mentagrophytesandM. canisin mice. It also reduces lesion size in a guinea pig model ofC. albicans infection. Formulations containing miconazole have been used in the treatment of various fungal infections.
1.Sawyer, P.R., Brogden, R.N., Pinder, R.M., et al.Miconazole: A review of its antifungal activity and therapeutic efficacyDrugs9(6)406-423(1975)
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