Carviolin 是从新保加利亚 pura 子囊菌菌丝体中分离出来的化合物。
货号:ajcx22008
CAS:478-35-3
分子式:C16H12O6
分子量：300.3
溶解度:Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Carviolin is an anthraquinone fungal metabolite that has been found inZ. longicaudatawith immunosuppressive and antitrypanosomal activities.^1,2It inhibits LPS- or concanavalin A-induced proliferation of mouse splenocytes (IC₅₀s = 4 and 4.5 µg/ml, respectively).¹Carviolin is active againstT. b. brucei(MIC = 41.66 µM).²

1.Fujimoto, H., Nakamura, E., Okuyama, E., et al.Six immunosuppressive features from an ascomycete, Zopfiella longicaudata, found in a screening study monitored by immunomodulatory activityChem. Pharm. Bull. (Tokyo)52(8)1005-1008(2004) 2.Aly, A.H., Debbab, A., Clements, C.M., et al.NF kappa B inhibitors and antitrypanosomal metabolites from endophytic fungus Penicillium sp. isolated from Limonium tubiflorumBioorg. Med. Chem.19(1)414-421(2011)