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2-Amino-3,4-dimethyl-3H-imidazo[4,5-f]quinoline
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
2-Amino-3,4-dimethyl-3H-imidazo[4,5-f]quinoline图片
规格:98%
分子量:212.3
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
A mutagenic heterocyclic amine
货号:ajcx21244
CAS:77094-11-2
分子式:C12H12N4
分子量:212.3
溶解度:Methanol: Slightly Soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

2-Amino-3,4-dimethyl-3H-imidazo[4,5-f]quinoline is a mutagenic heterocyclic amine that has been found in cooked foods.1,2,3It is mutagenic toS. typhimuriumin the Ames test.3Dietary administration of 2-amino-3,4-dimethyl-3H-imidazo[4,5-f]quinoline (0.03%) induces tumor formation in the Zymbal gland, oral cavity, and colon in male and female rats, the skin of male rats, and the mammary gland in female rats.1


1.Kato, T., Migita, H., Ohgaki, H., et al.Induction of tumors in the Zymbal gland, oral cavity, colon, skin and mammary gland of F344 rats by a mutagenic compound, 2-amino-3,4-dimethylimidazo[4,5-f]quinolineCarcinogenesis19(3)601-603(1989) 2.Johansson, M.A., and JÄgerstad, M.Occurrence of mutagenic/carcinogenic heterocyclic amines in meat and fish products, including pan residues, prepared under domestic conditionsCarcinogenesis15(8)1511-1518(1994) 3.Nagao, M., Sato, S., and Sugimura, T.Mutagens produced by heating foodsThe Maillard reaction in foods and nutrition521-536(1983)