BAY-6035 是一种有效的、选择性的和底物竞争性的 SMYD3 抑制剂。 BAY-6035 抑制 MEKK2 肽的甲基化，IC50 为 88 nM。
货号:ajcx19318
CAS:2247890-13-5
分子式:C22H28N4O3
分子量：396.5
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

BAY-6035 is an inhibitor of SET and MYND domain-containing protein 3 (SMYD3). It is 100-fold selective for SMYD3 over other histone methyltransferases. BAY-6035 inhibits methylation of MEKK2 peptide in a cell-free assay and in cells (IC50s = 88 and 70 nM, respectively). See the Structural Genomic Consortium (SGC) website for more information.

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