SR18662 是一种有效的 Kruppel-like factor 5 (KLF5) 的抑制剂， IC50 为 4.4 nM，ML264 的类似物。SR18662 可用于结直肠癌治疗的相关研究。
货号:ajcx17238
CAS:N/A
分子式:C16H19Cl2N3O4S
分子量：420.31
溶解度:DMSO: 125 mg/mL (297.40 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

SR18662 is a potent inhibitor of KrÜppel-like factor five (KLF5) with an IC50 of 4.4 nM, an analogue of ML264 with improved inhibitory potency against colorectal cancer cells. SR18662 can be used for the study of colorectal cancer[1].

[1]. Julie Kim,et al.The Novel Small-Molecule SR18662 Efficiently Inhibits the Growth of Colorectal Cancer In Vitroand In Vivo.Mol Cancer Ther.2019 Nov;18(11):1973-1984.