P62-mediated mitophagy inducer 是一种线粒体自噬调节剂，能激活线粒体噬但不招募 Parkin 或者使膜电位崩溃，且在缺乏完整功能的 PINK1/Parkin 通路的细胞中保留活性。
货号:ajcx14972
CAS:1809031-84-2
分子式:C14H9IN4O2
分子量：392.15
溶解度:DMSO: 1 mg/mL (2.55 mM; ultrasonic and adjust pH to 3 with 0.1 M HCL)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

P62-mediated mitophagy inducer is a mitophagy regulator which activates mitophagy without recruiting Parkin or collapsing δψm and retains activity in cells devoid of a fully functional PINK1/Parkin pathway[1].

[1]. East DA, et al. PMI: a δψm independent pharmacological regulator of mitophagy. Chem Biol. 2014 Nov 20;21(11):1585-96.