SNIPER(ABL)-020，由 Dasatinib (ABL 抑制剂) 通过 linker 与 Bestatin (IAP 配体) 组合而成，可有效降解 BCR-ABL 蛋白。
货号:ajcx39880
CAS:N/A
分子式:C44H59ClN10O8S
分子量：923.52
溶解度:DMSO : 200 mg/mL (216.56 mM; Need ultrasonic)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

SNIPER(ABL)-020, conjugating Dasatinib (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein[1].

[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.